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Clinafloxacin
Gatifloxacin
Gemifloxacin
Moxifloxacin
Pazufloxacin
Sparfloxacin
Tosufloxacin
Trovafloxacin

Second generation fluoroquinolones

The newer derivatives are being targeted at the treatment of respiratory infections in the community and, although they are undoubtedly effective, it is not clear if this use is wise. Indeed, there is already evidence that indiscriminate use of fluoroquinolones is undermining the effectiveness of these valuable drugs by encouraging resistance, notably in Gram-negative bacilli and pneumococci.

This generation of quinolones include: Clinafloxacin, Gatifloxacin, Gemifloxacin, Moxifloxacin, Pazufloxacin, Sparfloxacin, Tosufloxacin, Trovafloxacin.

 

 

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