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Cefazolin
Cefacetrile
Cefadroxil
Cefalexin
Cefaloglycin
Cefalonium
Cefaloridine
Cefalotin
Cefapirin
Cefatrizine
Cefazedone
Cefazaflur
Ceforadine
Cefroxadine
Ceftezole
Cephradine

First generation cephalosporins

The first generation cephalosporins include: Cefazolin, Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazaflur, Ceforadine, Cefroxadine, Ceftezole.

Cephalosporins in this group are of limited clinical value and have been largely superseded by other derivatives. Cefazolin has the unusual property of being excreted in fairly high concentration in bile; cefamandole exhibits a modestly expanded spectrum. Others, including cefapirin, ceforanide, and second generation cefonicid, offer no discernible advantage over earlier congeners such as cefalotin.


 

 

 

 

 

 

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