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Cycloserine

Cycloserine has broad-spectrum, but rather feeble antibacterial activity. It is now used only against multiresistant Mycobacterium tuberculosis. The drug bears a structural resemblance to the D-isomer of alanine and inhibits alanine racemase. It also blocks the synthetase enzyme that links two D-ala molecules together before they are inserted into the cell wall.

 

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