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Carbenicillin
Temocillin
Ticarcillin

Carboxypenicillins

Carboxypenicillins, like ureidopenicillins, were developed for effectiveness against enterobacteriaceae (Klebsiella species, Proteus species, Enterobacter species and Pseudomonas aeruginosa). Carbenicillin was developed by adding a carboxyl group to the penicillin molecule. Ticarcillin was developed by adding additional substitutions to the carbenicillin carboxyl group. Ticarcillin exhibits greater antipseudomonal activity than carbenicillin. Ticarcillin is not acid-stable, therefore the drug is administered parenterally.

 

 

 

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