Hit generation and validation

At the beginning of a research project scientist are asked to identify new chemical entities, that are able to act on a defined biological target. There are many possible ways to achieve this objective, based on rational, empirical or statistical approaches. Choosing the right methodology for the specific situation is crucial and should consider several aspects, including scientific knowledge, strategy, cost, timelines, available resources.

Key Benefits

  • Identification of active compounds suitable for optimization   
  • Validation of pharmacological target
  • Novel patentable compounds



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